Pyridoxal-5-phosphate (PLP) is the active form of vitamin B6, a water-soluble vitamin that is necessary for numerous biochemical reactions in the body. It is an essential nutrient, meaning that the body cannot produce it on its own and must obtain it from food or supplements.
PLP is a coenzyme, which means it is an organic molecule that helps enzymes carry out their functions. PLP is involved in over 150 enzymatic reactions, including the metabolism of carbohydrates, proteins, and fats. It is also involved in the synthesis of neurotransmitters, such as serotonin and dopamine, and in the production of red blood cells.
PLP is found in a variety of foods, including fish, poultry, meat, potatoes, bananas, and chickpeas. It is also available as a dietary supplement, typically in the form of pyridoxal-5-phosphate or as pyridoxine hydrochloride, which the body converts into PLP.
PLP is also known as pyridoxal phosphate, P-5-P, and PL. Its Latin name is pyridoxal-5-phosphoricum.
In terms of differences between different versions, pyridoxine hydrochloride is the most commonly available form of vitamin B6, but it must be converted by the body into PLP to be effective. PLP is the active form of vitamin B6, meaning that it is readily available for use by the body.
PLP has several health benefits. It has been shown to improve symptoms of PMS, reduce inflammation, improve mood and cognitive function, and support heart health. A study published in the Journal of Nutrition found that high doses of vitamin B6, including PLP, could reduce the risk of heart disease in women.
The recommended dosage for PLP varies depending on the individual’s age and health status. The National Institutes of Health recommends a daily intake of 1.3-1.7 mg for adults. However, higher doses may be needed for people with certain medical conditions, such as premenstrual syndrome or cardiovascular disease. It is always recommended to consult with a healthcare professional before taking any dietary supplements, including PLP
